Necrotizing Soft Tissue Infections

/Necrotizing Soft Tissue Infections

A number of types of infections of soft tissue may benefit from adjunct treatment with hyperbaric oxygen and are included in the category of “necrotizing soft tissue infections.” Names of such clinical syndromes include crepitant anaerobic cellulitis, progressive bacterial gangrene, necrotizing fasciitis, and nonclostridial myonecrosis. Gas gangrene (clostridial myositis and myonecrosis) is a separate entity. Necrotizing soft tissue infections themselves may induce conditions adverse to control of the infection by normal host defense mechanisms. The infections commonly lower tissue oxygen levels, impairing the ability of the white blood cells (neutrophils) to fight infection. Toxins produced by bacteria involved may also inhibit neutrophil activity. The primary treatments for necrotizing soft tissue infection are surgical excision of infected tissue and administration of appropriate antibiotics. Hyperbaric oxygen may be beneficial in several ways. Some of the bacteria involved in necrotizing soft tissue infections are “anaerobic,” growing most rapidly in a low oxygen environment. In the hyperbaric chamber, tissue oxygen levels may be raised sufficiently to inhibit bacterial growth. In addition, hyperbaric oxygen treatment may enhance the ability of neutrophils to kill bacteria, by a number of different mechanisms.

By | 2020-07-17T08:21:07-04:00 July 17th, 2020|0 Comments

CORONA VIRUS UPDATE

During this pandemic, we will try and minimize risks to patients and staff. Guidance changes frequently, so we may need to change our recommendations over time.

We ask that all patients come into the office wearing a mask. Masks may be removed at the instruction of the staff for hyperbaric oxygen therapy.

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